We have just completed rolling out MS Project Server 2010 in our organization, but it was a clean implementation – no upgrade from a previous version where I would be able to help you with upgrade path questions.
There were two people involved in the implementation, the SharePoint Administrator and myself. To prepare, we took a class on Installing and Deploying Project Server 2010 from MSProjectExperts which was very helpful in understanding what needed to be done to get the application up and running.
